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Addition Therapeutics is on a mission to fulfill the transformative promise of genomic medicine for people impacted by both chronic and rare diseases. Leveraging our breakthrough all-RNA, non-viral, LNP-based PRINT™ platform, we are overcoming the limitations of existing genetic medicine modalities to develop safer, durable, one-time therapies. Bolstered by our team of top-tier scientists and engineers, we are advancing a robust pipeline of PRINTed therapeutics that have the potential to fundamentally redefine how chronic and rare diseases are treated. Our investor syndicate includes SR One, Pivotal Life Sciences, Abingworth, Osage University Partners, the Gates Foundation, and BEVC.

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Addition Therapeutics is pioneering the future of genomic medicine by harnessing the innovative all-RNA PRINT™ platform. Committed to transforming healthcare, the company aims to make genomic therapies accessible to a broader range of patients, particularly those suffering from chronic and rare diseases. The PRINT technology leverages non-viral, lipid nanoparticle-based methods to deliver precise RNA-mediated treatments, offering a safer and more durable alternative to traditional genetic medicine.

With a dedicated team of skilled scientists and engineers, Addition is actively developing a promising pipeline of PRINTed therapeutics targeting significant unmet medical needs. Their research is supported by collaborations with pharmaceutical companies and notable organizations like the Gates Foundation, showcasing the platform's versatility in addressing various health challenges. By focusing on creating one-time therapies, Addition Therapeutics seeks to redefine treatment paradigms and improve patient outcomes, ultimately striving to fulfill the promise of genomic medicine for all.

Addition Therapeutics

Health

Biotechnology and Pharmaceuticals

Heavy Industry and Engineering

Chemical Industry

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Addition Therapeutics is at the forefront of biotechnology innovation, advancing transformative therapies utilizing its proprietary PRINT™ (Precise RNA-mediated Insertion of Transgenes) platform. PRINT™ redefines genetic medicine by enabling development of RNA-only therapeutics capable of inserting any genetic element into specific safe harbor sites within the genome. Operating from state-of-the-art labs in South San Francisco, our team of experienced scientists and drug developers is leading scientific breakthroughs while cultivating a vibrant, dynamic culture committed to profoundly impacting patient lives.

We’re looking for a Senior or Principal Data Engineer to design and implement the data infrastructure and systems that will power our data-driven discovery. You’ll play a defining role in how data is collected, organized, and made usable across the company. The ideal candidate will possess significant experience with developing data management systems and solutions in an early stage biotech environment. They will be highly collaborative and resourceful, with a keen interest in laying solid data foundations for future growth. This role has great potential to grow with the company, both technically and in scope of impact, and can contribute to paving the way for novel therapeutics that could redefine the landscape of genetic medicine. This role requires onsite presence at least 4 days per week.

## Responsibilities

- Data Infrastructure Management: design, develop, and maintain data repositories.
- Data Pipeline Development: build and maintain scalable data pipelines that extract, transform, and load (ETL) data from diverse sources.
- Data Quality & Governance: ensure data accuracy, consistency, and reliability, and implement policies for data security and privacy.
- System Monitoring & Optimization: monitor system performance, troubleshoot issues, and implement optimizations to improve the efficiency and reliability of data systems.
- Collaboration: work closely with experimentalists to understand how data is generated, and with data scientists to understand that data is used - and then create data management solutions that are fit-for-purpose for both.

## Qualifications

- Bachelor’s or Master’s degree in Computer Science, Engineering, or a related technical field.
- 3+ years of experience in data engineering including time spent in a biotech R&D environment with a commitment to FAIR data practices.
- Proven experience designing and maintaining ETL/ELT pipelines and cloud data architectures (e.g., AWS S3, Redshift, GCP BigQuery, Snowflake).
- Proficiency in Python and SQL, and familiarity with tools such as dbt, Airflow, or Prefect.
- Understanding of data modeling and best practices for structured and unstructured data.
- Comfort working in a small, fast-moving company with minimal existing infrastructure.
- Familiarity with modern development best practices - version control, testing, CI/CD, monitoring, and incident response.
- A collaborative mindset — excited to partner with scientists, data scientists, and leadership.
- (Bonus) Experience with omics data, LIMS systems (Benchling), or scientific data management.

## Compensation

The expected hourly rate for this contract position is $95.00-$100.00/hour. Exact compensation may vary based on skills and experience.

Senior/Principal Data Engineer

Snowflake

Store and retrieve any amount of data, at any time, from anywhere on the web

Amazon S3

dbt helps data teams work like software engineers—to ship trusted data, faster.

Fast, fully managed, petabyte-scale data warehouse service

Amazon Redshift

Data Infrastructure

Data Governance

System Monitoring

Data Quality

Principal Engineer

Data Architect

Senior Data Engineer

Contract Senior/Principal Data Engineer to design data infrastructure for biotech company

Addition Therapeutics

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