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Discover how Quotient is pioneering a new field of genetics with somatic genomics to unveil a universe of genetic information and develop new therapies.

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We transform somatic genomics insights into potentially breakthrough medicines. Learn more at Quotient-Tx.com

Research

Business Development

Engineering

Operations

United Kingdom

England, United Kingdom

United States

Greater Boston

Massachusetts, United States

Cambridge

Greater Cambridge Area

London Area, United Kingdom

Cambridge, MA

Greater London

Saffron Walden

Boston, MA

Quotient Therapeutics

Biotechnology and Pharmaceuticals

Health

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Quotient Therapeutics is a privately-held, early stage company developing breakthrough medicines informed by natural somatic genetic diversity present in patients. Through our work in somatic genomics, we are forging a new status quo for biopharma research and development across a broad pipeline of internal and partnered programs.

The company was founded by Flagship Pioneering, an innovative enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability.

**Position Summary:**
Quotient is seeking an experienced HR leader to serve as a fractional, part-time (3 days per week), on-site HR Consultant supporting our UK location. This is a consultant/independent contractor engagement, not a permanent employee position.

The HR Consultant will report directly to the Consultant VP of HR (US-based) and will operate as an embedded member of the global HR function during the term of the engagement.

This consultant will serve as the senior HR business partner to UK leadership, translating enterprise-wide people strategies into effective local execution while maintaining close collaboration with US-based HR leadership. This consultant will be the key HR thought partner to on-site leadership (C-level as well as R&D leadership team) in working to drive optimal team structure, a performance mindset, and a team-based culture.

The role requires disciplined alignment with enterprise HR governance, ensuring that all UK-based people practices, policies, and decisions are fully integrated with global standards and leadership oversight. This engagement does not establish a standalone or independent UK HR function; rather, the consultant will operate within an established global HR structure and decision-making framework.

The successful candidate will balance strategic insight with hands-on implementation in a dynamic, early-stage environment, helping to scale the organization while maintaining consistency, compliance, and cultural cohesion across geographies.

**Responsibilities:**

- Serve as the senior HR business partner for the UK site under a consulting engagement, reporting to and operating under the direction of the Consultant VP of HR (US-based)
- Serve as key thought partner to CSO and CDO, as well as members of their R&D leadership team, in continually evaluating their teams’ structures, manager and leadership effectiveness, and supporting a high performance team-based culture
- Execute and localize global HR strategies, policies, and programs in alignment with enterprise frameworks
- Ensure UK HR practices remain fully integrated with the broader global HR function
- Provide strategic input to UK leadership on organizational design, workforce planning, and talent strategy in coordination with global HR
- Lead performance management processes in alignment with company-wide frameworks
- Partner with the Consultant VP of HR on compensation planning, promotion processes, and talent reviews
- Advise leaders on employee relations matters, ensuring fair, consistent, and compliant practices under UK employment law
- Support talent acquisition strategy and hiring decisions in coordination with global recruiting processes
- Coach UK-based managers to strengthen leadership capability and reinforce company values
- Drive employee engagement and culture initiatives that reflect enterprise priorities
- Establish scalable and compliant HR processes appropriate for a growing UK workforce
- Contribute to global HR projects and initiatives as needed

**Qualifications:**
**Essential**

- Significant progressive HR leadership experience at the Director or Senior Director level
- Experience operating in a consulting, interim, or fractional HR leadership capacity strongly preferred
- Deep knowledge of UK employment law and HR best practices
- Demonstrated ability to operate effectively within an established HR governance structure
- Experience aligning local HR execution with global strategy
- Strong employee relations and leadership coaching expertise
- Ability to work independently while remaining highly collaborative and integrated
- Excellent communication and stakeholder management skills

**Desirable**

- Experience within life sciences, biotech, or high-growth organizations
- Experience working with US-based leadership teams
- Chartered MCIPD qualification or equivalent experience
- Experience supporting scientific or technical populations
- Prior exposure to venture-backed or early-stage environments

**Values and Behaviors:**

- Encourage respectful disagreement and cultivate open-minded, ego-free interactions to continuously push each other towards excellence
- Seek out diverse perspectives; practice active listening and genuine curiosity to ensure all contributions are valued, regardless of source
- Recognize the impact of your behavior, language and attitudes, and strive for balanced, meaningful exchanges that enhance mutual growth and understanding in all interactions
- Use a company-first mindset to guide decision-making; prioritize team over individual success
- Take calculated risks and challenge convention in the quest for exceptional outcomes

Director/Senior Director Human Resources (Fractional Consultant)

Human Resources

HR Business Partner

Human Resources Business Partner

Director of People Operations

Chief Human Resources Officer

Biopharma

Growth Stage

Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple transformative human health and sustainability products. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures. 

The current Flagship ecosystem comprises over 40 companies, including Denali Therapeutics, Foghorn Therapeutics, Generate:Biomedicines, Inari, Indigo Agriculture, and Tessera Therapeutics. 

Flagship Pioneering

We are a biotechnology company that invents and builds platform companies that change the world.

**Position Summary:**
Quotient is seeking an experienced HR leader to serve as a fractional, part-time (3 days per week), on-site HR Consultant supporting our UK location. This is a consultant/independent contractor engagement, not a permanent employee position.
  
  
The HR Consultant will report directly to the Consultant VP of HR (US-based) and will operate as an embedded member of the global HR function during the term of the engagement.
  
  
This consultant will serve as the senior HR business partner to UK leadership, translating enterprise-wide people strategies into effective local execution while maintaining close collaboration with US-based HR leadership. This consultant will be the key HR thought partner to on-site leadership (C-level as well as R&D leadership team) in working to drive optimal team structure, a performance mindset, and a team-based culture.
  
  
The role requires disciplined alignment with enterprise HR governance, ensuring that all UK-based people practices, policies, and decisions are fully integrated with global standards and leadership oversight. This engagement does not establish a standalone or independent UK HR function; rather, the consultant will operate within an established global HR structure and decision-making framework.
  
  
The successful candidate will balance strategic insight with hands-on implementation in a dynamic, early-stage environment, helping to scale the organization while maintaining consistency, compliance, and cultural cohesion across geographies.
  
  
**Responsibilities:**

- Serve as the senior HR business partner for the UK site under a consulting engagement, reporting to and operating under the direction of the Consultant VP of HR (US-based)
- Serve as key thought partner to CSO and CDO, as well as members of their R&D leadership team, in continually evaluating their teams’ structures, manager and leadership effectiveness, and supporting a high performance team-based culture
- Execute and localize global HR strategies, policies, and programs in alignment with enterprise frameworks
- Ensure UK HR practices remain fully integrated with the broader global HR function
- Provide strategic input to UK leadership on organizational design, workforce planning, and talent strategy in coordination with global HR
- Lead performance management processes in alignment with company-wide frameworks
- Partner with the Consultant VP of HR on compensation planning, promotion processes, and talent reviews
- Advise leaders on employee relations matters, ensuring fair, consistent, and compliant practices under UK employment law
- Support talent acquisition strategy and hiring decisions in coordination with global recruiting processes
- Coach UK-based managers to strengthen leadership capability and reinforce company values
- Drive employee engagement and culture initiatives that reflect enterprise priorities
- Establish scalable and compliant HR processes appropriate for a growing UK workforce
- Contribute to global HR projects and initiatives as needed

**Qualifications:**
**Essential**

- Significant progressive HR leadership experience at the Director or Senior Director level
- Experience operating in a consulting, interim, or fractional HR leadership capacity strongly preferred
- Deep knowledge of UK employment law and HR best practices
- Demonstrated ability to operate effectively within an established HR governance structure
- Experience aligning local HR execution with global strategy
- Strong employee relations and leadership coaching expertise
- Ability to work independently while remaining highly collaborative and integrated
- Excellent communication and stakeholder management skills

**Desirable**

- Experience within life sciences, biotech, or high-growth organizations
- Experience working with US-based leadership teams
- Chartered MCIPD qualification or equivalent experience
- Experience supporting scientific or technical populations
- Prior exposure to venture-backed or early-stage environments

**Values and Behaviors:**

- Encourage respectful disagreement and cultivate open-minded, ego-free interactions to continuously push each other towards excellence
- Seek out diverse perspectives; practice active listening and genuine curiosity to ensure all contributions are valued, regardless of source
- Recognize the impact of your behavior, language and attitudes, and strive for balanced, meaningful exchanges that enhance mutual growth and understanding in all interactions
- Use a company-first mindset to guide decision-making; prioritize team over individual success
- Take calculated risks and challenge convention in the quest for exceptional outcomes

**About Quotient:**
Quotient Therapeutics is a privately-held, early stage company developing breakthrough medicines informed by natural somatic genetic diversity present in patients. Through our work in somatic genomics, we are forging a new status quo for biopharma research and development across a broad pipeline of internal and partnered programs.
  
  
The company was founded by Flagship Pioneering, an innovative enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Generate Biomedicines, Sana Biotechnology (SANA), Tessera Therapeutics, Evelo Biosciences (EVLO), Indigo Agriculture, Seres Therapeutics (MCRB), and Syros Pharmaceuticals (SYRS).
  
  
Quotient Therapeutics and Flagship Pioneering are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Quotient Therapeutics is seeking a fractional, part-time HR Consultant for their UK location. The role involves serving as a senior HR business partner, aligning local HR execution with global strategies, and supporting leadership in driving a high-performance culture.

Fractional Director/Senior Director Human Resources

Quotient Therapeutics

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